Cretinism is a medical condition present at birth wherein there is a decreased or absent thyroid function and thyroid hormone production [1]. It can be caused due to a defect in the genes encoding various enzymes involved in thyroid hormone synthesis such as thyroglobulin, iodotyrosine deiodinase and … Cretinism Etiology. Lack of thyroid hormones is the cause. Myxoedematous or hypothyroid cretinism is less common and characterised by mental retardation (although less severe than in neurological cretinism), dwarfism, and hypothyroidism with associated physical symptoms (e.g., coarse and dry skin, husky voice, delayed sexual maturation). Cretinism is of 2 types: Congenital Cretinism. Cretinism is a medical condition caused by an untreated congenital thyroid hormone deficiency. Incidence is 1:3000 to 1:4000 in an iodine-deficient endemic area. Dwarfism. Iodization of table salt and early screening of babies has largely eliminated the condition from such regions. In some cases, it can happen spontaneously. In several hormonal disorders and hereditary conditions dwarfism is associated with subnormal intelligence. Inadequate production of thyroid hormone during gestation and early infancy results in a condition known as cretinism, which is characterized by growth retardation and … Bones and muscles may also degenerate. Causes of proportionate dwarfism include metabolic and hormonal disorders such as growth hormone deficiency. It causes mental retardation and dwarfism. It leads to mental and physical growth impairment. Dwarfism is usually the result of a genetic mutation. Continued Dwarfism Causes. It features dwarfism, mental retardation, dry skin, a large tongue and a puffy face. But if left untreated, patients may have stunted growth to the point of dwarfism. (C follows D)(cretins have disproportionate limbs) ... Cretinism is a type of hypothyroidism that occurs in infants or kids. Thyroid deficiency may result from: Iodine deficiency (in developing nations) It causes impaired neurological … Cretinism can be common, genetic or periodic. If untreated, it results in mild to severe impairment of both physical and mental growth and development. There are approximately 400 types of dwarfism. Newborns with Cretinism can be of normal weight and height. Cretinism occurs mainly in regions remote from the sea. It is present from birth. Hello Everyone, How do we differentiate between dwarfism and cretinism? When pituitary produces an insufficient amount of growth hormone, it retards the height of an individual. But having a gene or genes responsible for dwarfism can occur in a couple of ways. When untreated, this could lead to severely stunted physical and mental growth of the newborn [2]. cretinism A condition caused by thyroid underaction from severe iodine deficiency early in life. Congenital hypothyroidism, previously known as cretinism, is a severe deficiency of thyroid hormone in newborns. Growth hormone secreted by the pituitary gland is responsible for dwarfism or shortness. Just remember GIRL G- Growth- Reduced in both I- IQ- Normal in pituitary dwarfism and decreased in cretenism R-Reproduction-Absent or delayed puberty in bothL-Limbs- Proportionate in Dwarfs and Disproportionate in cretins.